Intracorneal Amphotericin B Injection in a Case of Indolent Candidal Keratitis
Published: May 1, 2017 | DOI: https://doi.org/10.7860/JCDR/2017/23249.9774
Jyoti Deswal, Sudesh Kumar Arya
1. Senior Resident, Department of Ophthalmolgy, GMCH, Chandigarh, India.
2. Professor, Department of Ophthalmology, GMCH, Chandigarh, India.
Correspondence
Dr. Jyoti Deswal,
Senior Resident, Department of Ophthalmolgy, H.NO. 25/10-A, Jasbir Colony (Near Sheela By-Pass), Rohtak-124001,
Haryana, India.
E-mail: jyoti_deswal@yahoo.co.in
Ocular candidiasis is one of the opportunistic infection occurring in human body. Pathogenesis wise, Candida is very virulent and slow growing organism. We report a case of 76-year-old female with left eye candidal stromal abscess, not responding to topical and oral antifungal drugs. Patient was administered intrastromal amphotericin B injection in the affected eye. Four midstromal injections were given in the areas surrounding the corneal abscess. A total of approximately 0.05 mL of amphotericin B, 5 µg per 0.1 mL, was administered. Within next four weeks, the eye became completely quiet with healed epithelial defect and corneal scarring. Intracorneal injection of amphotericin B is a safe and effective treatment option for recurrent and recalcitrant fungal infections.
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